Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p41 | Bone biomechanics and quality | ECTS2016

Investigation of the potential link between mechanosensory proteins PC1/PC2 and craniosynostosis

Katsianou Maria , Piperi Christina , Korkolopoulou Penelope , Themistocleous Marios S , Basdra Efthimia K , Papavassiliou Athanasios G

Background: Skull development is a tightly regulated process that occurs along the osteogenic interfaces of the cranial sutures that allow rapid bone formation at the edges of the bone fronts. Premature closure of cranial sutures can result in pathological conditions such as Craniosynostosis. The mechanosensory proteins Polycystin 1 (PC1) and 2 (PC2) have been shown to regulate skeletal development and potentially suture formation.Aim: The aim of study w...